Use of Ultrasound and Anterior Segment Optical Coherence Tomography to Compare Central Corneal Thickness Values in Patients with Open Angle Glaucoma

Main Article Content

Panagiotis Tsikripis
Fryni Riga
Maria Stamatiou

Abstract

Purpose: To compare central corneal Thickness (CCT) using ultrasound (US) pachymetry and Anterior Segment Optical Coherence Tomography (AS-OCT), in patients with open-angle glaucoma (OAG).

Methods: Ninety patients above 50 years with healthy corneas were prospectively included for repeated measurements of central corneal Thickness (CCT), using ultrasound pachymetry (US) and Anterior Segment Optical Coherence Tomography (AS-OCT), during the same visit. The readings were averaged and compared by paired t-test. Both eyes of each participant were measured for our study.

Results: Ultrasound pachymetry showed significantly higher CCT values. The CCT measured by AS-OCT and ultrasound was 525 ± 32.1 μm and 533 ± 38 μm respectively for the right eye. For the left eye the values were 523 ± 31.2 μm and 532 ± 33.1 μm respectively for the AS-OCT and US. The difference in CCT measurement by AS-OCT and ultrasound was statistically significant (P<0.001) in both eyes with mean standard deviation of ultrasound CCT being 16.14 µm greater than the mean of AS-OCT CCT for the right and 15.12 μm for the left eye. A strong correlation was found (r >0.80) between the CCT measurement techniques. The Anova test didn’t reveal serious differences neither with AS-OCT, nor with US pachymetry.

Conclusion: Central Cornea Thickness measurement by ultrasound pachymetry gives higher values compared to AS-OCT measurement in patients with OAG. This in clinical practice means, that they cannot be interchangeably used and both must be considered as methods of examination.

 

Keywords:
Primary open-angle glaucoma, pachymetry, central corneal thickness, anterior segment optical coherence tomography

Article Details

How to Cite
Tsikripis, P., Riga, F., & Stamatiou, M. (2018). Use of Ultrasound and Anterior Segment Optical Coherence Tomography to Compare Central Corneal Thickness Values in Patients with Open Angle Glaucoma. Ophthalmology Research: An International Journal, 8(4), 1-7. https://doi.org/10.9734/OR/2018/40561
Section
Original Research Article