Intra Ocular Lens Technology - A Review of Journey from Its Inception

Main Article Content

Ragni Kumari
Mrinal Ranjan Srivastava
Pragati Garg
Rajiv Janardhanan


Aim: To understand the advancement and development in Intraocular lens.

Introduction: Now a day cataract surgery is the most commonly performed surgical procedure in the world. Removing the opaque, cataractous lens and replacing it with an artificial lens to achieve near to normal visual acuity post operatively is not only accepted but by and large a mandatory norm.

Findings: The lenses used for the purpose are called Intra Ocular Lens. Ridley’s brilliance has improved the lives of many millions of people. The gradual improvement in IOL design, first in making flexible lenses, then the ever-improving optical outcomes have meant that vision after cataract surgery has never been better – in the developed world.

Conclusion: We have come a long way in terms of IOL design, but many people with cataracts in rural areas of the developing world, need help to catch up.

Cataract, extra capsular, ntracapsular, surgery, IOL (Intraocular Lens Implant).

Article Details

How to Cite
Kumari, R., Ranjan Srivastava, M., Garg, P., & Janardhanan, R. (2020). Intra Ocular Lens Technology - A Review of Journey from Its Inception. Ophthalmology Research: An International Journal, 11(3), 1-9.
Review Article


Apple DJ, Auffarth GU, Peng Q, Visessook N. Foldable intraocular lenses: Evolution, clinicopathologic correlations, and complications. Slack (Publ.); 2000.
ISBN: 1556424353, 9781556424359.

Auffarth GU, Apple DJ. History of the development of intraocular lenses. Ophthalmologe. 2001;98:1017–28.

Auffarth GU, Schmidbauer J. Intraocular lenses. Ophthalmologe. 2001;98(11): 1011.

Beasley AM, Auffarth GU, von Recum AF. Intraocular lens implants: A biocompatibility review. J. Invest. Surg. 1996;9:399–413.

Auffarth GU, Wilcox M, Sims JC, et al. Analysis of 100 explanted one-piece and three-piece silicone intraocular lenses. Ophthalmology. 1995;102:1144–50.

Ridley NHL. The cure of aphakia, 1949. Intraocular lens implantation. Rosen, Haining and Arnott, C.V. Mosby, Toronto. 1984;37–41.

Zhou KY. Silicon intraocular lenses in 50 cataract cases. Chinese Medical Journal. 1983;96:175–176.

Apple DJ. Sir Harold Ridley and his fight for sight: He changed the world so that we may better see it. Slack (Publ.). ISBN 1-55642-786-7; 2006.

Shankar C, From the Pages of History. History of intra ocular lens. Chettinad Health City Medical Journal. 2016;5(1):54-55.

Ridley NHL. Further experiences of intraocular acrylic lens surgery. Br. J. Ophthalmol. 1954;38:156–162.

Ridley NHL. Intraocular acrylic lenses – past, presence and future. Trans. Ophthalmol. Soc. UK. 1964;84:5–14.

Jay Yohendran. Intraocular lenses: A practical review for optometrists. 2 CPD in Australia, 1G in New Zealand; 2018.

Achieving Excellence in Cataract Surgery A Step-by-Step Approach Edited by D. Michael Colvard, MD, FACS Clinical Professor of Ophthalmology Doheny Eye Institute Keck School of Medicine University of Southern California Los Angeles, CA Medical Director of Colvard Eye Center Encino, CA.

Findl O, Kriechbaum K, Koeppl C, et al. Laserinterferometric measurement of the movement of an ‘accommodative’ intraocular lens. In: Guthoff R, Ludwig K, Eds. Current Aspects of Human Accommodation II. Heidelberg, Germany: Dr. Reinhard Kaden Verlag; 2003.

Koeppl C, Findl O, Menapace R, et al. Pilocarpine-induced shift of an accommodating intraocular lens: AT-45 Crystalens. J Cataract Refract Surg. 2005;31(7):1290-1297.

Hancox J, Spalton D, Heatley C, et al. Objective measurement of intraocular lens movement and dioptric change with a focus shift accommodating intraocular lens. J Cataract Refract Surg. 2006;32(7):1098-1103.

Findl O. Intraocular lenses for restoring accommodation: Hope and reality. J Refract Surg. 2005;21(4):321-323.

Hollick EJ, Spalton DJ, Ursell PG, et al. The effect of polymethylmethacrylate, silicone, and polyacrylic intraocular lenses on posterior capsular opacification 3 years after cataract surgery. Ophthalmology. 1999;106(1):49-54.

Ursell PG, Spalton DJ, Pande MV, et al. Relationship between intraocular lens biomaterials and posterior capsule opacification. J Cataract Refract Surg. 1998;24(3):352-360.

Sundelin K, Friberg-Riad Y, Ostberg A, Sjostrand J. Posterior capsule opacification with AcrySof and poly(methyl methacrylate) intraocular lenses. Comparative study with a 3-year follow-up. J Cataract Refract Surg. 2001;27(10): 1586-1590.

Hollick EJ, Spalton DJ, Ursell PG, Pande MV. Lens epithelial cell regression on the posterior capsule with different intraocular lens materials. Br J Ophthalmol. 1998;82(10):1182-1188.

Nishi O. Posterior capsule opacification. Part 1: experimental investigations. J Cataract Refract Surg. 1999;25(1):106-117.

Nishi O, Nishi K, Sakanishi K. Inhibition of migrating lens epithelial cells at the capsular bend created by the rectangular optic edge of a posterior chamber intraocular lens. Ophthalmic Surg Lasers. 1998;29(7):587-594.

Nishi O, Nishi K, Mano C, et al. The inhibition of lens epithelial cell migration by a discontinuous capsular bend created by a band-shaped circular loop or a capsule- bending ring. Ophthalmic Surg Lasers. 1998;29(2):119-125.

Findl O, Buehl W, Bauer P, Sycha T. Interventions for preventing posterior capsule opacification. Cochrane Database System Rev. 2007(3).

Buehl W, Menapace R, Findl O, et al. Long-term effect of optic edge design in a silicone intraocular lens on posterior capsule opacification. Am J Ophthalmol. 2007;143(6):913-919.

Buehl W, Findl O, Menapace R, et al. Long-term effect of optic edge design in an acrylic intraocular lens on posterior capsule opacification. J Cataract Refract Surg. 2005;31(5):954-961.

Leyland M, Zinicola E. Multifocal versus monofocal intraocular lenses after cataract extraction. Cochrane Database Syst Rev. 2003;3:CD003169.

Chernyak DA. Cyclotorsional eye motion occurring between wavefront measurement and refractive surgery. J Cataract Refract Surg. 2004;30(3):633-638.

Packer M, Fine IH, Hoffman RS, Piers PA. Prospective randomized trial of an anterior surface modified prolate intraocular lens. J Refract Surg. 2002;18: 692-696.

Mester U, Dillinger P, Anterist N. Impact of a modified optic design on visual function: Clinical comparative study. J Cataract Refract Surg. 2003;29(4):652-660.

Lisa B. Samalonis. Aspheric IOLs: From theory to practice if implanted properly, aspheric lenses may provide improved visual function over traditional spherical IOLs. Review of Ophthalmology.
(Published 15 June 2005)