Ophthalmology Research: An International Journal

Aim: The study aimed to evaluate the effect of 0.1% Nevanac drops used after uncomplicated cataract surgery on central macular thickness (CMT) and total macular volume (TMV).

Study Design: Observational study.

Place and duration study: Ahi Evran University Training and Research Hospital's Eye Clinic, between January-February 2018.

Methodology: This study included 60 eyes of 60 patients who underwent cataract surgery. Phaco surgery under topical anaesthesia was performed on all patients. The eyes were randomly divided into two groups after the surgery. Only standard topical medication was administered to the control group (32 eyes) while standard topical medication, as well as topical Nevanac 0.1% TID, were used for the Nevanac group (28 eyes) for one month. The patients’ preop, postop, 1^st week and 1^st- month CMT and TMV were measured automatically by optical coherence tomography (OCT). A p- value <0.05 was accepted as statistically significant value.

Results: When both groups were evaluated in terms of CMT, no statistically significant difference was present between the preop, 1^st week and 1^st- month measurements (p= 0.337, p= 0.742, p= 0.921, respectively). When the two groups were compared regarding TMV, no statistically significant difference was found between preop, 1^st week and 1^st- month measurements (p= 0.729, p= 0.13, p= 0.105, respectively). As regards CMT, there was no significant difference between preop values and 1^st week and 1^st- month measurements in the Nevanac group, but a significant difference was present between the preop measurements and first- month measurements in the control group (p<0.001). When the total macular volumes were compared in the Nevanac group, a statistically significant difference was found between the preop and 1^st- month measurements (p<0.001). A statistically significant difference was found between the preop values and both the 1^st week and 1^st- month measurements in the control group (p<0.001).

Conclusion: In conclusion, central macular thickness and total macular volume showed a small increase compared to preop values when 0.1% Nevanac was used after uncomplicated cataract surgery.