New Marker for Suspected Open Globe Injury (Perforation or Penetration): Neutrophil-to-lymphocyte Ratio and Platelet-to-lymphocyte Ratio
Kenan Yiğit *
Department of Ophthalmology, Antalya Education and Research Hospital, Sağlik Bilimleri University, Antalya, Turkey and Department of Ophthalmology, Faculty of Medicine, Afyonkarahisar Health Sciences University, Afyonkarahisar, Turkey.
Reşat Duman
Department of Ophthalmology, Faculty of Medicine, Afyonkarahisar Health Sciences University, Afyonkarahisar, Turkey and Department of Ophthalmology, Bursa City Hospital, Bursa, Turkey.
Rahmi Duman
Department of Ophthalmology, Faculty of Medicine, Afyonkarahisar Health Sciences University, Afyonkarahisar, Turkey and Department of Ophthalmology, Liv Hospital, Ankara, Turkey.
Zubeyir Yozgat
Department of Ophthalmology, Faculty of Medicine, Afyonkarahisar Health Sciences University, Afyonkarahisar, Turkey and Department of Ophthalmology, Ardahan State Hospital, Ardahan, Turkey.truer
Ersan Çetinkaya
Department of Ophthalmology, Antalya Education and Research Hospital, Sağlik Bilimleri University, Antalya, Turkey and Department of Ophthalmology, Faculty of Medicine, Afyonkarahisar Health Sciences University, Afyonkarahisar, Turkey.
Mehmet Cem Sabaner
Department of Ophthalmology, Faculty of Medicine, Afyonkarahisar Health Sciences University, Afyonkarahisar, Turkey.
*Author to whom correspondence should be addressed.
Abstract
Purpose: To compare the strength of the relationship between the neutrophil-to-lymphocyte ratio (NLR) and platelet-to-lymphocyte ratio(PLR) results of patients with or without open globe injury (perforation and penetration) in the acute period of orbital trauma.
Materials and Methods: Forty patients with open globe injuryand twenty-five patients without open globe injury in the acute period of orbital trauma were enrolled in this retrospective study. Complete blood count measurement results of all subjects were assessed.
Results: There was a significant difference in neutrophil-to-lymphocyte ratio and the platelet-to-lymphocyte ratio between orbital trauma with open globe injury group and without open globe injury group (p=0.001, p=0.006).
Conclusion: Our results of the blood count measurements suggest that the NLR and PLR at first three hours may predict ocular perforation/penetration and the clinicians have to alert are a risk factor of open globe injury.
Keywords: Orbital perforation, neutrophil, lymphocyte, platelet.