The Beneficial Effects of Photobiomodulation to Reduce Intraocular Pressure in Primary Open-Angle Glaucoma

A. Chaoui Boudghene *

SARL Laboratory Neurogenesis Research and Development, Mostaganem, Algeria and EURL Clinique Dar El Bassar, Mostaganem, Algeria.

T. I. Braik Ahmed

SARL Laboratory Neurogenesis Research and Development, Mostaganem, Algeria.

K. Belbachir

SARL Laboratory Neurogenesis Research and Development, Mostaganem, Algeria.

H. Benkazdali Ghalia

SARL Laboratory Neurogenesis Research and Development, Mostaganem, Algeria.

*Author to whom correspondence should be addressed.


Purpose: The aim of this trail was to study the efficacy of photobiomodulation (PBM) treatment to reduce the intraocular pressure in subjects with primary open angle glaucoma disease.

Methods: Twenty eyes suffering from open angle glaucoma with high IOP level were selected, examined and treated with Thera-RED light diode system. The subjects were divided into two groups (n=10); treated and placebo group respectively; this system provide two lights (red at 660n.m continue and Near IR light micro-pulsed at 850 n.m), the patients received two series of treatment (ten per month within three months between every series of sessions) over five months and follow up taking ocular pressure measurements after every diode delivery session.

Results: A significant decrease in IOP has been observed from the first month of the treatment compared to the placebo group (from 22.6mmHg before treatment to 15 mmHg after the tenth session) this amelioration has been also remarked during the second session of treatment (fifth month) to attempt 14.2 mmHg. 

Conclusion: Thera-RED light diode system  treatment shows a significant  decrease of  IOP and remained to be stable under 14.2 mmHg in all the follow up, which  confirm that photobiomodulation  help in reducing   the intraocular pressure  in glaucomatous patients .

Keywords: Photobiomodulation, intra ocular pressure, trabecular meshwork, diode light, primary open angle glaucoma, aqueous humor

How to Cite

Boudghene , A. C., Ahmed , T. I. B., Belbachir , K., & Ghalia, H. B. (2023). The Beneficial Effects of Photobiomodulation to Reduce Intraocular Pressure in Primary Open-Angle Glaucoma. Ophthalmology Research: An International Journal, 18(3), 17–26.


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