Neurological-Onset Vogt–Koyanagi–Harada Disease with Delayed Ocular Involvement: An Atypical Case with Favorable Outcome
Asmae Najah *
Department of Ophthalmology, Arrazi Hospital, Mohammed VI University Hospital Center, Marrakech, Morocco.
Niama El Fahli
Department of Ophthalmology, Arrazi Hospital, Mohammed VI University Hospital Center, Marrakech, Morocco.
Hind Safi
Department of Ophthalmology, Arrazi Hospital, Mohammed VI University Hospital Center, Marrakech, Morocco.
Soumia Allaoui
Department of Ophthalmology, Arrazi Hospital, Mohammed VI University Hospital Center, Marrakech, Morocco.
Younes Tlemcani
Department of Ophthalmology, Arrazi Hospital, Mohammed VI University Hospital Center, Marrakech, Morocco.
Sarah Belghmaidi
Department of Ophthalmology, Arrazi Hospital, Mohammed VI University Hospital Center, Marrakech, Morocco.
Abdeljalil Moutaouakil
Department of Ophthalmology, Arrazi Hospital, Mohammed VI University Hospital Center, Marrakech, Morocco.
*Author to whom correspondence should be addressed.
Abstract
Vogt–Koyanagi–Harada Disease is an uncommon systemic autoimmune disorder that predominantly affects young adults. Its diagnosis relies on a combination of clinical and paraclinical findings, but may be delayed because of atypical presentations. We report the case of a 26-year-old woman initially managed for idiopathic intracranial hypertension, in whom the subsequent development of bilateral granulomatous panuveitis associated with exudative retinal detachment led to the diagnosis of incomplete VKH disease. Early initiation of high-dose corticosteroid therapy combined with immunosuppressive treatment resulted in complete visual recovery. This case highlights the importance of early diagnosis in improving visual prognosis and preventing progressive complications.
Keywords: Vogt-Koyanagi-Harada disease, panuveitis, neurological presentation, optical coherence tomography, systemic corticosteroids, immunosuppressive therapy, visual prognosis