Phenothiazine Group Drug Induced Corneal and Lenticular Deposits in a Patient of Severe Depression – A Case Report
Ojha Sushil *
Department of Ophthalmology, UP RIMS and R, Saifai, Etawah, UP, India
Tandon Anupama
Department of Ophthalmology, UP RIMS and R, Saifai, Etawah, UP, India
Saraswat Neeraj
Department of Ophthalmology, UP RIMS and R, Saifai, Etawah, UP, India
Shukla Dipendra
Department of Ophthalmology, UP RIMS and R, Saifai, Etawah, UP, India
*Author to whom correspondence should be addressed.
Abstract
A 50-yr-old man, who had been taking medication for severe depression with psychosis, presented to eye OPD of UPRIMS & R with a chief complaint of visual disturbance of 8 months duration. He was continuously taking chlorpromazine unsupervised in double the dose and doubles the frequency. Slit-lamp examination revealed fine, discrete, and brownish deposits on the posterior cornea. In addition, bilateral star-shaped anterior sub capsular lens opacities, which were dense, dust-like granular deposits, were noted. Best-corrected visual acuity was 6/36 in the right eye and 6/24 in the left eye. Other ocular findings were normal. Dark pigmentation on face was present. The deposition was not reversible even after stopping the drug.
Keywords: Corneal deposits, drug induced lenticular opacity, phenothiazine induced deposits