Ophthalmology Research: An International Journal https://journalor.com/index.php/OR <p style="text-align: justify;"><strong>Ophthalmology Research: An international Journal (ISSN:&nbsp;2321–7227)</strong> aims to publish high quality papers (<a href="/index.php/OR/general-guideline-for-authors">Click here for Types of paper</a>) in all areas of ‘Ophthalmology research’. The journal also encourages the submission of useful reports of negative results. This is a quality controlled,&nbsp;OPEN&nbsp;peer reviewed, open access INTERNATIONAL journal.</p> SCIENCEDOMAIN international en-US Ophthalmology Research: An International Journal 2321-7227 Detection of Visual Field Loss Progression in Glaucoma: An Overview and Food for Thought https://journalor.com/index.php/OR/article/view/30158 <p>The damage to the visual field is the main outcome of glaucoma. Basically, there are two different approaches to establish the rate of the functional loss in this clinical condition: event-based analysis and trend-based analysis. The event-based analysis, that relies on the occurrence of pre-established events to detect the progression of the visual field damage, cannot quantify the decay rate of sensitivity. In turn, the trend-based analysis, that aims to measure the rate of progression according to linear regression models, requires a long follow-up. Despite considerable effort, there is still no consensus on the optimal procedure, and a gold standard is still missing. This paper provides a quick overview of the topic as a tribute to the researchers engaged in this field.</p> Carlo Aleci ##submission.copyrightStatement## 2020-07-02 2020-07-02 16 24 10.9734/or/2020/v13i130158 Effect of Yellow Filters and Corrective Lenses on Academic Performance of Primary School Children with Abnormal Contrast Sensitivity https://journalor.com/index.php/OR/article/view/30156 <p><strong>Aim:</strong> This study compared the effect of yellow filters and corrective lenses on the academic performance of primary school children with abnormal contrast sensitivity.</p> <p><strong>Study Design: </strong>The study employed quantitative study design involving the measurement of variables.</p> <p><strong>Place and Duration of Study: </strong>This study was carried out in Owerri North, Imo State, Nigeria, from February, 2019 to November, 2019.</p> <p><strong>Methodology: </strong>The study included 34 children between 7-12 years old in private and public schools with abnormal contrast sensitivity comprising 7-9 year-olds (64.7%); 10-12 year-olds (35.3%); Males (52.9%) and Females (47.1%). Using basic optometric procedures and Pelli-Robson contrast sensitivity chart, children with abnormal contrast sensitivity were identified for the study. Academic performance was assessed by comparing the previous midterm summative test result (pre-test) with the current midterm summative test result (post-test).</p> <p><strong>Results:</strong> Paired sample t-Test showed no significant difference in academic performance of children using corrective lenses (<em>p</em> = .47), and those using corrective lenses with yellow filters (<em>p </em>= .94) respectively at 95% confidence interval. Also, children using corrective lenses compared with those using corrective lenses with yellow filters showed no significant difference (<em>p</em> =.57) in academic performance. Further, no significant age and gender variation in academic performance was identified (7-9 yrs: <em>p</em> =.38; 10-12 yrs: <em>p</em> =.79; Males: <em>p</em>=.38; Females: <em>p</em> =.79).</p> <p><strong>Conclusion:</strong> Corrective lenses and Corrective lenses with yellow filters had no effect on academic performance of primary school children 7-12 years of age with abnormal contrast sensitivity.&nbsp;</p> C. J. Samuel- Nwokeji N. C. Ikoro E. C. Esenwah A. U. Megwas Y. C. Azuamah N. C. Ibe U. C. Ogbonna ##submission.copyrightStatement## 2020-06-25 2020-06-25 1 11 10.9734/or/2020/v13i130156 The Effect of Anti-Tubercular Drugs on Retinal Nerve Fiber Layer Thickness Using Optical Coherence Tomography https://journalor.com/index.php/OR/article/view/30157 <p><strong>Purpose</strong><strong>:</strong> To study the effect of anti-tubercular drugs on retinal nerve fiber layer (RNFL) thickness using optical coherence tomography.</p> <p><strong>Methods</strong><strong>:</strong> The study was done in thirty patients newly diagnosed with pulmonary tuberculosis which were given anti-tubercular treatment (isoniazid, rifampicin, ethambutol and pyrazinamide ) at DOTS centre of K. N. TB and Chest hospital (Dr. S.N M C.) Jodhpur. Visual function tests (visual acuity, contrast sensitivity, color vision) and OCT assessment of RNFL done before initiation of treatment and after two month of treatment.</p> <p><strong>Results</strong><strong>:</strong> After two months, RNFL thinning was present in 3 eyes out of total 60 eyes in temporal and superior quadrant.</p> <p><strong>Conclusion</strong><strong>:</strong> The study revealed that the first line antitubercular drug Ethambutol causes RNFL thinning within two months of initiation of drug in the recomonded dose. In the initial stage of optic nerve toxicity, there are no clinically significant changes seen on posterior segment ophthalmoscopic examination and fundus photography.OCT can find out the retinal nerve fiber layer thinning even if there are minute changes.</p> Punit Kumar Singh . Prasnnta ##submission.copyrightStatement## 2020-07-01 2020-07-01 12 15 10.9734/or/2020/v13i130157