Aims: To analyse the visual results and complications in sclera-fixated intraocular lenses with a four-point fixation technique.
Study Design: Case series
Place and Duration of Study: The study was conducted at Sarojini Devi Eye Hospital, which is a government medical college and tertiary eye care hospital in South India. The study was conducted between October 2013 and June 2016.
Methodology: A consecutive series of patients who had undergone secondary scleral-fixated intraocular lens (SF IOL) implantation in cases of aphakia with inadequate posterior capsular support was analysed. This is a modified four-point scleral fixation technique that is comprised of scleral tunnels to bury the suture knots and fix the IOL at four points on the sclera.
Results: The study was comprised of 30 eyes of 30 patients (17 men, 13 women). The mean age at surgery was 46.6 years (range of 8–83 years), and the mean follow-up was 19 months (range of 15–31 months). The corrected distance visual acuity was 6/24 (0.68 log mar units) preoperatively, which improved to 6/18(0.45 log mar units) postoperatively. The most common postoperative complication was raised intraocular pressure, which was seen in 13 eyes (43.6% P value <0.0001).
Conclusions: The results of the study indicate that SF IOL is a promising option in cases of aphakia with no capsular support, as the technique has minimal complications when conducted properly.
Aim: To assess the final visual outcome after Intraocular Lens (IOL) implantation in children with traumatic cataract.
Materials and Methods: Retrospective study, Twenty five children with traumatic cataract age ranging from 2 years to 14 years over the period of two years were selected after fulfilling the inclusion criteria. A thorough systemic and ocular examination was carried out. This included recording of visual acuity, anterior segment examination, slit lamp biomicroscopy, tonometry, posterior segment evaluation with B-scan ultrasonography.IOL power, Keratometry was done with the help of Keratometer (KM- 500, NIDEK) and IOL power was calculated with the help of A-scan (Alcon, Ocuscan) using Sanders Retzlaff Kraff (SRK) –II formula and IOL Master (Carl Zeiss Meditec. AG).
Results: 19 (76%) male and 6 female (24%).14 patients (56%) were suffered from penetrating injury, of this 10 (71.4%) were male, 4 (28.6%) were female. There were 11 patients (44%) who suffered blunt injury of this 9 (81.8%) were male and 2 (18.18%) were female. Most common mode of penetrating injury was by stick. Preoperative visual acuity was < 1/60 in 20 cases (80 %). The final visual outcome with the best correction was 6/6 in 4 (16 %) cases (3 in blunt, 1 in penetrating), 6/9 in 4 cases (16%) cases. CONCLUSION- intraocular lens implantation in children has a role in treating aphakia, resulting in good visual outcome and binocularity.
Aim: To compare the effects of cruciate and circular Neodymium: yttrium-aluminum-garnet (Nd: YAG) laser posterior capsulotomy techniques on the thickness of retinal layers measured by spectral domain optical coherence tomography (SD-OCT).
Study Design: A prospective cohort, clinical study
Setting Single surgery, Afyon Kocatepe University Hospital, TR.
Materials and Methods: 28 pseudophakic patients with the posterior capsule opacification were included in this prospective pilot study. Age- and sex-matched 2 groups were formed and either cruciate or circular technique for Nd: YAG laser posterior capsulotomy was applied to each group. All patients were examined 1 week and 1 month after the capsulotomy. Best corrected visual acuity (BCVA), intraocular pressure (IOP) and retinal layer thickness measurements by OCT were recorded precapsulotomy and at the following visits. Mean shot energy and number, total laser energy, IOP, BCVA and OCT findings were compared between 2 groups.
Results: Despite the higher number of laser shots and total laser energy applied in circular technique group, no significant difference of central macular thicknesses at 1000, 3000, and 6000 mm was observed between two techniques.
Conclusion: The cruciate technique may be suggested to be safer than the circular technique in terms of amount of used energy. The short-term effects on the retinal layers seem to be similar in both techniques.
Aim: Although there has been ongoing evidence about the role of inflammation in the pathophysiology of pterygium, exact inflammatory pathogenesis is not known. Cytosolic phospholipase A2 (cPLA2) is an inflammatory enzyme taking a role in various physiological and pathological responses. The present study aimed to investigate the expression of cPLA2 in human pterygium tissues.
Materials and Methods: Expressions of cPLA2 were analyzed by immunohistochemistry in biopsy specimens of 20 pterygium and 10 normal conjunctival tissues. Expression patterns and staining intensities were compared between pterygium and normal tissues.
Results: Intense expression of cPLA2 was present in all normal conjunctival tissues (100%) whereas no expression was detected in 5 pterygium cases (25%), and in the remaining pterygium tissues (75%) mild/ moderate expression of cPLA2 was shown. Furthermore, expression was shown throughout the epithelium being more intense in the superficial layers in normal conjunctivas, whereas it was mainly located in basal layers in pterygium tissues.
Conclusion: Downregulated expression of cPLA2 in pterygium tissues compared to normal conjunctiva shown in the present study supports the role of inflammatory enzymes in the formation of pterygium. cPLA2 enzyme seems to have a protective role against pterygium formation.