Open Access Original Research Article

The Outcomes of Primary Retinal Detachment Surgery with 23-gauge Vitrectomy in Patients without Severe Proliferative Vitreoretinopathy: A Single Surgeon Case Series

Abdullah Ozkaya, Hatice Nur Tarakcioglu, Burcu Kemer

Ophthalmology Research: An International Journal, Page 1-6
DOI: 10.9734/OR/2018/41843

Aims: To evaluate the outcomes of vitrectomy in patients with primary rhegmatogenous retinal detachment (RRD) without a significant proliferative vitreoretinopathy (PVR).

Study Design: Retrospective, interventional, single-surgeon case series.

Place and Duration of the Study: Beyoglu Eye Training and Research Hospital, Istanbul, Turkey, between January 2013 and December 2016.

Materials and Methods: The patients who underwent vitrectomy for RRD with grade A or B PVR with a follow up period of at least 12 months, and had a post-silicone oil (SO) removal follow-up of at least 6 months (if SO was used as a tamponade) were included. Functional success was defined to have a postoperative best corrected visual aculity ≥ 1.0 LogMAR, and anatomical success was defined to have an attached retina after postoperative month 6 in patients with gas tamponade or after post-silicone oil removal month 6 in patients with silicone oil tamponade. The primary outcome measure of this study was the anatomical success rate after a single surgery.

Results: A total of 85 eyes of 85 patients were included. The mean follow-up period was 16.8±5.7 months. Single operation success was obtained in 78 of the 85 patients (91.8%). The recurrent retinal detachment was detected in 7 patients (8.2%). All of the patients were operated again and at the last follow-up visit final anatomical success was achieved in 83 of the 85 patients (97.6%), the remaining 2 patients (2.4%) had attached macula and they were planned to left with permanent silicone oil tamponade.

Conclusion: Vitrectomy is an effective method in the treatment of primary RRD without significant PVR.

 

Open Access Original Research Article

The Effect of Cataract Surgery on the Intraocular Pressure in Eyes with and without Pseudoexfoliation Syndrome

Salma M. Kedwany, Ashraf K. Al-Hussaini, Ehab I. Wasfi, Mohamed Sharafeldin

Ophthalmology Research: An International Journal, Page 1-8
DOI: 10.9734/OR/2018/42660

Aims: To determine the effect of cataract surgery on the intraocular pressure (IOP) in eyes with and without pseudoexfoliation syndrome (PXF).

Study Design:  prospective, non-randomized, age-matched controlled, clinical study.

Place and Duration of Study: Department of Ophthalmology, Assiut University Hospital, Assiut; Egypt, between January 2015 to December 2016.

Methodology: This study included two groups of non-glaucomatous eyes with visually significant senile cataract:  32 eyes with PXF (PXF group), 32 eyes without PXF (control group).  In each group, planned extracapsular cataract extraction (PECCE) was done in 22 eyes and phacoemulsification was done in 10 eyes. IOP was measured at one week, one month and three months postoperatively and compared to the preoperative values.

Results: The difference in mean preoperative IOP between PXF group (14.53±3.253 mmHg) and the control group (13.97±2.335 mmHg) was insignificant (P=0.69). A significantly lower postoperative IOP (P<0.001) than the preoperative level was detected at all follow-up visits in both groups. Mean IOP reduction was significantly greater in PXF group than in the control group at one month (P=0.014) and three months (P=0.012) postoperatively.

Conclusion: IOP significantly decreased after cataract surgery in eyes with and without PXF for up to three months postoperatively. This decrease was significantly greater in PXF group than in the control group at one month and three months postoperatively.

 

Open Access Original Research Article

Visual Function Outcomes in Tinted versus Non- Tinted IOLs in Cataract Patients

Prateek Koul, Sachit Mahajan, Satish Gupta

Ophthalmology Research: An International Journal, Page 1-9
DOI: 10.9734/OR/2018/44228

Aims: The study aims to compare the visual function outcomes in tinted versus non-tinted IOL in cataract patients.

Study Design: Prospective, randomised, clinical study was conducted on patients.

Place and Duration of Study: The study was carried out at Upgraded Department of Ophthalmology, Government Medical College Jammu, India during November 2016 to October 2017.

Methodology: This study included two groups of 100 patients each. 100 patients in group 1 were randomly implanted with tinted IOLs, and another 100 patients in group 2 were implanted with non-tinted IOLs. Visual functions such as Best Corrected Visual Acuity (BCVA), Colour Vision (CV) and Contrast Sensitivity (CS) were compared after 1st post-operative day, 2nd week and 3rd month.

Results: The mean changes between the uncorrected visual acuity (UCVA) (day 1) and best corrected visual acuity (3rd month) reveals a non significant change between the two groups, however, the mean change in tinted group was more than nontinted groups i.e. 76.17% (p =0.101). Pre- and Post-operative colour vision remained same in both the groups and mean change in contrast sensitivity after day 1 and contrast sensitivity (3rd month) also revealed a non significant change, however mean change in tinted group was more (64.55%) in compared to non-tinted group (33.28%) with p value of 0.283.

Conclusion: The mean change in best corrected visual acuity and contrast sensitivity is statistically insignificant for both the groups.

 

Open Access Original Research Article

The Effect of 0.1% Nevanac on Macular Thickness and Volume after Uncomplicated Cataract Surgery

Özkan Kocamış, Ali Kurt, Raşit Kılıç, Osman Ahmet Polat

Ophthalmology Research: An International Journal, Page 1-7
DOI: 10.9734/OR/2018/43990

Aim: The study aimed to evaluate the effect of 0.1% Nevanac drops used after uncomplicated cataract surgery on central macular thickness (CMT) and total macular volume (TMV).

Study Design: Observational study.

Place and duration study: Ahi Evran University Training and Research Hospital's Eye Clinic, between January-February 2018.

Methodology: This study included 60 eyes of 60 patients who underwent cataract surgery. Phaco surgery under topical anaesthesia was performed on all patients. The eyes were randomly divided into two groups after the surgery. Only standard topical medication was administered to the control group (32 eyes) while standard topical medication, as well as topical Nevanac 0.1% TID, were used for the Nevanac group (28 eyes) for one month. The patients’ preop, postop, 1st week and 1st- month CMT and TMV were measured automatically by optical coherence tomography (OCT). A p- value <0.05 was accepted as statistically significant value.

Results: When both groups were evaluated in terms of CMT, no statistically significant difference was present between the preop, 1st week and 1st- month measurements (p= 0.337, p= 0.742, p= 0.921, respectively). When the two groups were compared regarding TMV, no statistically significant difference was found between preop, 1st week and 1st- month measurements (p= 0.729, p= 0.13, p= 0.105, respectively). As regards CMT, there was no significant difference between preop values and 1st week and 1st- month measurements in the Nevanac group, but a significant difference was present between the preop measurements and first- month measurements in the control group (p<0.001). When the total macular volumes were compared in the Nevanac group, a statistically significant difference was found between the preop and 1st- month measurements (p<0.001). A statistically significant difference was found between the preop values and both the 1st week and 1st- month measurements in the control group (p<0.001).

Conclusion: In conclusion, central macular thickness and total macular volume showed a small increase compared to preop values when 0.1% Nevanac was used after uncomplicated cataract surgery.

 

Open Access Review Article

The Pathogenesis of Index Myopia in Hyperglycemia in Type 2 Diabetes: A Review

Benedict C. Umezurike, Okechukwu Udeala, Uzoamaka G. Green, Ugonma Okpechi-Agbo, Maureen U. Ohaeri

Ophthalmology Research: An International Journal, Page 1-17
DOI: 10.9734/OR/2018/42436

Elevated blood glucose or hyperglycemia occasioned by Diabetes Mellitus (DM), compromises the index of refraction of the crystalline lens, due to the osmotic difference between the lens materials and the aqueous medium of the anterior chamber of the eye. Under this circumstance there is a movement of fluid to either direction depending on the concentration gradient in both media. When there is movement out of the lens, into the aqueous, the refractive index of the lens increases, and this situation also causes a sudden change in the refractive power of the lens, leading to index myopia, while a decrease leads to index hyperopia. However, the induced myopia from this sudden fluctuation in the refractive power of the crystalline lens reverses shortly after a prolonged treatment and control of the hyperglycemia, with a combination of hypoglycemic drugs and diet therapy by the physician. The Issuance of spectacle prescription during these fluctuations is suspended until reversal.