Open Access Case Report

Rare Case of Misdiagnosed Rathke Pouch Cleft Leading to Severe Visual Loss

Pradeep Tekade, Prashant Bulchandani, Nikhilesh Wairagade

Ophthalmology Research: An International Journal, Page 20-24
DOI: 10.9734/or/2022/v17i130248

A rare case of symptomatic Rathke cleft cyst resulting in severe visual compromise in a young 45 yr/f who presented with gradual progressive painless diminution of vision in both eyes. Patient noticed diminution of vision in the Left eye an year ago and later on in the Right eye for which she consulted ophthalmologists. She was diagnosed as optic neuritis and underwent treatment for the same, but vision didn’t improve. At presentation,vision in Both eyes was same, counting fingers at 2 meters. Pupillary reactions were normal, however there was bilateral disc pallor and rest fundus was normal. On systemic evaluation patient gave history of irregular menstrual periods since 3-4 months. on further investigation her S. Prolactin levels were markedly raised(59.99ng/ml). Radiology showed well defined hyperintense suprasellar lesion. Patient was operated for right frontotemporal craniotomy with decompression of RCCs by a neurosurgeon. 2 months post surgery visual acuity in RE 4/60 and LE is counting finger close to face.

Open Access Case study

Central Retinal Vein Occlusion as a Presenting Feature Caused by Hypertensive Crisis Secondary to IgA Nephropathy

Pradeep Tekade, Prashant Bulchandani, Nikhilesh Wairagade

Ophthalmology Research: An International Journal, Page 8-11
DOI: 10.9734/or/2022/v17i130246

We present a case of Ischemic Central retinal vein occlusion (CRVO) caused by hypertension secondary to renal failure in IgA nephropathy. A 17 year old male came with chief complaints of sudden painless diminution of vision in RE since 15 days. On examination the Right eye showed multiple superficial retinal haemorrhages in all 4 quadrents with dilated veins and cystoid macular edema suggestive of CRVO and Left eye showed superficial flame shaped haemorrhage suggestive of grade 3 hypertensive changes.

Open Access Original Research Article

Evaluation of Ocular Findings in Vitiligo

Najat Belkheir, Adam Albarghathi, Ghait Alsdae, Faraj Alshwin, Gamal Duweb

Ophthalmology Research: An International Journal, Page 1-7
DOI: 10.9734/or/2022/v17i130245

Vitiligo is a pigmentary disorder of the skin and mucous membranes with worldwide incidence of 0.5-2%. The aim of this cross sectional study was to assess the ocular involvement in vitiligo patients. Two hundred patients clinically diagnosed vitiligo attending vitiligo clinic, dermatology department, Jomhorya hospital, Benghazi-Libya over a period of 6 months enrolled in this cross-sectional study. All patients were exposed to detailed disease history and thorough dermatological examination. Out of the total cases, 100 patients had a standard Ophthalmologic examination in cooperation with an ophthalmologist in Benghazi eye hospital. Results of our study showed a slightly higher prevalence of vitiligo in females (male: female ratio 1:2.8). The mean age of onset for males was 22.4 years and for females 24.8 years and 58.5% of patients develop vitiligo below 20 years of age. Generalized vitiligo was the commonest clinical type of vitiligo (57.5%). The relationship between the duration of the disease and its type was statistically significant (P<0.05), there was also a significant relationship between the type of vitiligo and its severity (P< 0.01). Sixteen patients (8%) had segmental vitiligo and the face was the common site involved. The lower limbs were the most commonly affected sites of the body (57%). Ocular changes were seen in 40% of patients and specific ocular abnormalities like uveitis, iritis, and iris and retinal pigmentary abnormalities are present in 15% of patients, nonspecific ocular abnormalities were present in 33% of patients. There was no statistically significant correlation between specific ocular abnormalities, severity and duration of vitiligo.

Open Access Original Research Article

Use of Scheimpflug Tomography and OCT Tomography to Examine Corneal Dimensional and Anterior Chamber Depth before and after LASIK Surgery

Aikaterini E. Mouzaka, Themistoklis K. Gialelis, Haris Sideroudi, Kleonikos Tsakiris, Vassilios P. Kozobolis

Ophthalmology Research: An International Journal, Page 12-19
DOI: 10.9734/or/2022/v17i130247

Aims: The aim of this study is to compare corneal parameters in: central corneal thickness (CCT), thinnest corneal thickness (TCT), mean radius of curvature (Rm) and anterior chamber depth (ACD) obtained from Pentacam Schiempflug and OCT Tomography imaging which are checked preoperatively and six months postoperatively after LASIK surgery.

Methodology: Our sample consisted of 40 eyes. Changes in corneal dimensions were monitored before and after LASIK surgery using scheimpflug tomography (Pentacam HR) and optical coherence tomography (OCT). The parameters measured were CCT, TCT, Rm and the ACD. The results between the two techniques were compared with the Bland-Altman method.

Results: During the analysis of the results, a statistically significant difference was observed between the two techniques in terms of the preoperative CCT as well as the TCT both preoperatively and postoperatively.

Scheimpflug tomography gives higher values of the CCT than OCT, up to thickness 530nm, while above this it seems that OCT overestimates the thickness of the cornea. Scheimpflug tomography at the TCT seems to give higher values than OCT tomography, up to thickness 520 nm, while above that it seems that OCT tomography overestimates TCT. We have similar results postoperatively for TCT.

The two techniques agree on the ACD and the Rm rating.

Conclusion: How converging or different the two imaging devices are because it is important for both clinical practice and research may be a point of reference for starting a new research.

Open Access Original Research Article

Analysis of 74 Open Globe Injuries Requiring Vitreo-Retinal Intervention and Its Correlation with Ocular Trauma Score

Girish A. Gadre, Prashant Bulchandani

Ophthalmology Research: An International Journal, Page 25-29
DOI: 10.9734/or/2022/v17i130249

Aim: Retrospective study of 74 eyes with open globe injuries requiring V-R Intervention & its correlation with ocular trauma score.

Results: Commonest cause of injury: Hammer-chisel/stone in 32.43% (24) & Thorn/wooden stick 27% (20). Average age-30.5yrs. Average interval between trauma & intervention was -10.04days (4hrs – 52days).

Discussion: Delay of presentation to ophthalmologist has lot of significance,high incidence of endophthalmitis & retinal detachment compared to other studies. Surgical outcome shows lower incidence of NO Light Perception & Significant reduction in number of cases with </=HM. Patients had better prognosis & visual outcome, higher incidence of 1/200- 20/50; 35.14% cases with >20/200. 60% of our cases had traumatic cataract, visual acuity may be underestimated in traumatic cataract. Faulty Projection of rays probably would be better criteria than RAPD. Extension of wound beyond pars plana, and aniridia (6.7%) are important risk factor.

Conclusion: Modification of raw points is recommended in OTS criteria in Indian scenario.