Primary Orbital Lymphoma – A Rare Challenging Diagnostic Entity
Nisha Marwah
Department of Pathology, PGIMS, Rohtak, India.
Niti Dalal *
Department of Pathology, PGIMS, Rohtak, India.
Manali Satiza
Department of Pathology, PGIMS, Rohtak, India.
Sunita Singh
Department of Pathology, PGIMS, Rohtak, India.
*Author to whom correspondence should be addressed.
Abstract
The diagnosis of lymphoproliferative disorder of orbit is quite challenging as both Pseudolymphomas and Non‑Hodgkin’s lymphomas can occur in orbit. Primary orbital lymphoma is a rare entity comprising of 1-2% of Non‑Hodgkin’s lymphoma, majority of them are B‑cell type. It is a slow growing tumor. It presents in the age group of 50–70 years, with a slight female preponderance. Proptosis is the most common presentation. We, herein, report a case of 48 years old male presenting with right non-axial proptosis, watering of eye, blurring of vision and redness for the last 9 months. After thorough clinical and radiological evaluation, a biopsy was taken for histopathological examination. A primary diagnosis of Lymphoproliferative Disorder was made. Following this, a panel of immunohistochemical markers was applied and a final diagnosis of Non-Hodgkin Lymphoma, B-cell type was given.
Keywords: Primary, non hodgkin’s lymphoma, B cell type, orbit.